cryoSPARC Optimized GPU Systems

Developed by Structura Biotechnology Inc., cryoSPARC is the state-of-the-art platform used globally for obtaining 3D structural information from single particle cryo-EM data.

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EDU Discounts Available

Purchase a qualifying NVIDIA GPU-powered workstation or server from Exxact and gain exclusive EDU discounts.

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Wide NVIDIA Platform Selection

Exxact offers a wide selection of workstation and server platforms to meet the individual compute needs of each customer's unique use case.

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Standard 3 Year Warranty

Have peace of mind, focus on what matters most, knowing your system is backed by a 3 year warranty and support.

cryoSPARC Workstations

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Entry-Level
TWS-1642706-CRS

Base Specs
CPU1x Intel Core i9
GPU2x NVIDIA TITAN RTX, or up to 4x NVIDIA RTX A6000 or RTX 8000/6000
MEMUp to 256GB DDR4 Memory
STOUp to 8x 3.5" Hot Swap Drive Bays
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Mid-Range
TWS-115999024-CRS

Base Specs
CPU2x 3rd Gen Intel Xeon Scalable (Silver)
GPUUp to 4x NVIDIA A100, RTX A6000, A40, or RTX 8000/6000 GPUs
MEMUp to 4TB DDR4 Memory
STOUp to 8x 3.5" Hot Swap Drive Bays
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High-End
TWS-115999024-CRS

Base Specs
CPU2x 3rd Gen Intel Xeon Scalable (Gold)
GPUUp to 4x NVIDIA A100, RTX A6000, A40, or RTX 8000/6000 GPUs
MEMUp to 4TB DDR4 Memory
STOUp to 8x 3.5" Hot Swap Drive Bays

cryoSPARC Servers

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Entry-Level
TS2-197278655-CRS

Base Specs
CPU2x 3rd Gen Intel Xeon Scalable CPUs
GPUUp to 4x NVIDIA A100, RTX A6000, A40, or RTX 8000/6000 GPUs
MEMUp to 2TB DDR4 Memory
STO8x 3.5" Hot-swap drive bays
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Mid-Range
TS4-672702-CRS

Base Specs
CPU2x Intel Xeon Scalable CPUs
GPUUp to 10x NVIDIA A100, RTX A6000, A40, or RTX 8000/6000 GPUs
MEMUp to 1.5TB DDR4 Memory
STO24x 2.5" Hot-Swap Drive Bays
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High-End
TS4-173535991-CRS

Base Specs
CPU2x AMD EPYC 7002 CPUs
GPUUp to 10x NVIDIA A100, RTX A6000, A40, or RTX 8000/6000 GPUs
MEMUp to 4TB DDR4 Memory
STO24x 2.5" Hot-swap drive bays

Not sure what you need?

Let us know what kind of project you have planned. We can help you decide.

Accomplish the impossible

AlphaFold + RoseTTAFOLD
Available now

Leverage the power of AI for protein folding in your research today.

CryoSPARC Live

Keep pace with data collection with CryoSPARC Live

CryoSPARC Live™ is an extension of the cryoSPARC platform that enables real-time cryo-EM data quality assessment and decision making during live data collection, as well as an expedited, streamlined workflow for processing already available data.

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GPU Accelerated cryo-EM with cryoSPARC Workstations and Servers

cryoSPARC is the state-of-the-art platform used globally for obtaining 3D structural information from single-particle cryo-EM data. The cryoSPARC optimized servers and workstations from Exxact enable automated, high quality, and high-throughput structure discovery of proteins, viruses, and molecular complexes for research and drug discovery.


Key cryoSPARC Features

  • Pre-processing of microscope data, including global and local motion correction, estimation of microscope parameters, curation and culling of individual micrographs
  • Particle picking, sorting, and classifying 2D images to remove low-quality information
  • Ab-initio 3D structure determination of homogeneous and heterogeneous samples, without the need for prior knowledge of the structure or conformations present
  • Refinement of 3D structures to near-atomic resolution, with specialized algorithms for membrane proteins and difficult cases
  • Post-processing of maps for use in atomic modeling

cryosparc workflow

Relion GPU Systems

Accelerate the most computationally intensive processes of Relion Cryo-EM such as image classification, and high-resolution refinement and achieve dramatic improvements in performance, while reducing TCO.


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