GPU Accelerated Cryo-Electron Microscopy

Relion is an image processing software designed specifically for cryo-electron microscopy (cryo-EM). Developed by the group of Sjors Scheres at the MRC Laboratory of Molecular Biology, the Relion framework is revolutionizing the cryo-EM field. It is a stand alone computer program built for the refinement of macromolecular structures by single-particle analysis of electron cryo-microscopy data. Relion employs an empiracal Bayesian approach for refinement of multiple 3D reconstructions or 2D class averages. With alternative approaches often relying on user expertise for the tuning of parameters, Relion can find an optimal way of filtering the data automatically.

GPU Accelerated Cryo-EM Pipeline

With Exxact Relion GPU Systems, users can address the most computationally intensive steps of the cryo-EM structure determination workflow. Processes such as image classifcation and high-resolution refinement can achieve a dramatic speed up in computing time by using one of our systems.

Relion Iteration GPU vs CPU Comparison